mass spectrometry, mass spectrometry, mass spectrometry, proteomics , proteomics, mass spectrometry, mass spectrometry, proteomics


selected recent publications :

Schwahn AB, Wong JWH, Downard KM (2009) Signature peptides of influenza nucleoprotein for the typing and subtyping of the virus by high resolution mass spectrometry, Analyst, 134: 2253- 2261.

Schwahn AB, Wong JWH, Downard KM (2009) Subtyping of the Influenza Virus by High Resolution Mass Spectrometry, Anal. Chem., 81: 3500–3506

Wong JWH, Schwahn AB, Downard KM (2009) ETISEQ - an algorithm for automated elution time ion sequencing of concurrently fragmented peptides for mass spectrometry-based proteomics, BMC Bioinformatics, 10: 244.

Schwahn AB, Downard KM (2009) Antigenicity of a type A influenza virus through comparison of hemagglutination inhibition and mass spectrometry immunoassays, J. Immunochem. Immunoassay, 30, 245-261.

Downard KM, Morrissey B (2009) An Immunoproteomics Approach to Screen the Antigenicity of the Influenza Virus, in Methods in Molecular Biology: Immunoproteomics (Ed. A.W. Purcell), in press.

Diemer H, Atmanene C, Sanglier S, Morrissey B, Van Dorsselaer A, Downard KM (2009) Detection and structural features of the B2-B3-crystallin heterodimer by radical probe mass spectrometry (RP-MS), J. Mass Spectrom., 44: 803-812.

Downard KM, Morrissey B, Schwahn AB (2009) Mass Spectrometry Analysis of the Influenza Virus, Mass Spectrom. Rev. 28: 35-49.

Morrissey B Downard, KM (2008) Kinetics of Antigen-Antibody Interactions Employing a MALDI Mass Spectrometry Immunoassay, Anal. Chem., 80, 7720-7726.

Morrissey B, Streamer M, Downard KM (2007) Antigenic Characterisation of H3N2 subtypes of the Influenza Virus by Mass Spectrometry, J. Virol. Methods, 145, 106–114.

Downard KM (ed.) (2007) Mass Spectrometry of Protein Interactions, John Wiley & Sons, New Jersey U.S.A. (ISBN 978-0-471-79373-1).

Downard KM (2007) Softly. Softly. Detection of Protein Complexes by Matrix-assisted Laser Desorption Ionization Mass Spectrometry, in Mass Spectrometry of Protein Interactions, John Wiley & Sons, New Jersey U.S.A., pp. 25-43.

Maleknia SD, Downard KM (2007) Genesis and Application of Radical Probe Mass Spectrometry (RP-MS) to Study Protein Interactions, in Mass Spectrometry of Protein Interactions, John Wiley & Sons, New Jersey U.S.A., pp. 109-133.

Downard KM, Morrissey B (2007) Fingerprinting a Killer - Surveillance of the Influenza Virus by Mass Spectrometry, The Analyst, 132, 611–614.

Ho JWK, Morrissey B, Downard KM (2007) A Computer Algorithm for the Identification of Protein Interactions from the Spectra of Masses (PRISM), J. Am. Soc. Mass Spectrom., 18, 563–566.

Downard KM (2006) Ions of the Interactome - The Role of Mass Spectrometry in the Study of Protein Interactions in Proteomics and Structural Biology, Proteomics, 6: 5374-5384.


Gerega SK, Downard KM (2006) PROXIMO - A New Docking Algorithm to Model Protein Complexes Using Data from Radical Probe Mass Spectrometry, Bioinformatics, 22: 1702-1709.

Issa S, Downard KM (2006) Interaction between Alpha and Upsilon-Crystallin Common to the Eye of the Australian Platypus by Radical Probe Mass Spectrometry, J. Mass Spectrom., 41: 1298-1303.


Morrissey B, Downard KM (2006) A Proteomics Approach to Survey the Antigenicity of the Influenza Virus by Mass Spectrometry, Proteomics, 6: 2034-2041.

Maleknia SD, Downard KM (2005) Charge ratio analysis method to interpret high resolution electrospray Fourier transform-ion cyclotron resonance mass spectra, Int. J. Mass Spectrom. 246, 1-9.

Wong JWH, Maleknia SD, Downard KM (2005) Hydroxyl Radical Probe of the Calmodulin-Melittin Complex Interface by Electrospray Ionization Mass Spectrometry, J. Am. Soc. Mass Spectrom., 16: 225-233

Shum W-K, Maleknia SD, Downard KM, (2005) Onset of Oxidative Damage in α-Crystallin by Radical Probe Mass Spectrometry, Anal. Biochem., 344: 247-256.

Maleknia SD, Downard KM (2005) Charge Ratio Analysis Method: Approach for the Deconvolution of Electrospray Mass Spectra, Anal. Chem., 77: 111-119.

Wong JWH, Downard KM, (2005) Performance of the Computer Algorithm COMPLX for the Detection of Protein Complexes in the Mass Spectra of Simulated Biological Mixtures, J. Mass Spectrom., 40: 1187-1196.

Downard KM (2004) Mass Spectrometry - A Foundation Course, Royal Society of Chemistry (ISBN 0-85404-609-7).


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