Professor Jules Mitchell Guss

Professor Molecular and Microbial Biosciences Faculty of Science G08 - Biochemistry and Microbiology Building The University of Sydney NSW 2006 Australia Email Click here Phone +61 2 9351 4302 Fax +61 2 9351 4726		Quick Links List Profiles Update Your Profile How to update your profile

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• Langley, D, Harty, D, Jacques, N, Hunter, N, Guss, J, Collyer, C. Structure of N-acetyl-beta-D-glucosaminidase (GcnA) from the Endocarditis Pathogen Streptococcus gordonii and its Complex with the Mechanism-based Inhibitor NAG-thiazoline. Journal of molecular biology. 2008; 0:0 [Abstract]
• Bhati, M, Lee, C, Nancarrow, A, Lee, M, Craig, V, Bach, I, Guss, J, Mackay, J, Matthews, J. Implementing the LIM code: the structural basis for cell type-specific assembly of LIM-homeodomain complexes. The EMBO journal. 2008; 27:2018-29 [Abstract]
• Langley, D, Brown, D, Cheruzel, L, Contakes, S, Duff, A, Hilmer, K, Dooley, D, Gray, H, Guss, J, Freeman, H. Enantiomer-specific binding of ruthenium(II) molecular wires by the amine oxidase of Arthrobacter globiformis. Journal of the American Chemical Society. 2008; 130:8069-78 [Abstract]
• Bhati, M, Lee, M, Nancarrow, A, Bach, I, Guss, J, Matthews, J. Crystallization of an Lhx3-Isl1 complex. Acta crystallographica. Section F, Structural biology and crystallization communications. 2008; 64:297-299 [Abstract]
• Langley, D, Shojaei, M, Chan, C, Lok, H, Mackay, J, Traut, T, Guss, J, Christopherson, R. Structure and inhibition of orotidine 5'-monophosphate decarboxylase from Plasmodium falciparum. Biochemistry. 2008; 47:3842-54 [Abstract]

• Lee, M, Maher, M, Christopherson, R, Guss, J. Kinetic and Structural Analysis of Mutant Escherichia coli Dihydroorotases: A Flexible Loop Stabilizes the Transition State(,). Biochemistry. 2007; 46:10538-10550 [Abstract]
• Lee, M, Chan, C, Graham, S, Christopherson, R, Guss, J, Maher, M. Structures of Ligand-free and Inhibitor Complexes of Dihydroorotase from Escherichia coli: Implications for Loop Movement in Inhibitor Design. Journal of molecular biology. 2007; 370:812-825 [Abstract]
• Whitten, A, Jacques, D, Hammouda, B, Hanley, T, King, G, Guss, J, Trewhella, J, Langley, D. The structure of the KinA-Sda complex suggests an allosteric mechanism of histidine kinase inhibition. Journal of molecular biology. 2007; 368:407-20 [Abstract]
• Lee, M, Maher, M, Guss, J. Structure of the T109S mutant of Escherichia coli dihydroorotase complexed with the inhibitor 5-fluoroorotate: catalytic activity is reflected by the crystal form. Acta crystallographica. Section F, Structural biology and crystallization communications. 2007; 63:154-161 [Abstract]

• Duff, A, Shepard, E, Langley, D, Dooley, D, Freeman, H, Guss, J. A C-terminal disulfide bond in the copper-containing amine oxidase from pea seedlings violates the twofold symmetry of the molecular dimer. ACTA CRYSTALLOGRAPHICA. 2006; 62:1168-73 [Abstract]
• Jeffries, C, Graham, S, Stokes, P, Collyer, C, Guss, J, Matthews, J. Stabilization of a binary protein complex by intein-mediated cyclization. Protein science : a publication of the Protein Society. 2006; 15:2612-8 [Abstract]
• Langley, D, Duff, A, Freeman, H, Guss, J. The copper-containing amine oxidase from Arthrobacter globiformis: refinement at 1.55 and 2.20 A resolution in two crystal forms. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY AND CRYSTALLIZATION COMMUNICATIONS. 2006; 62:1052-7 [Abstract]
• Duff, A, Cohen, A, Ellis, P, Hilmer, K, Langley, D, Dooley, D, Freeman, H, Guss, J. The 1.23 A structure of Pichia pastoris lysyl oxidase reveals a lysine-lysine cross-link. Acta crystallographica. Section D, Biological crystallography. 2006; 62:1073-84 [Abstract]
• Graham, S, Lilley, P, Lee, M, Schaeffer, P, Kralicek, A, Dixon, N, Guss, J. Kinetic and crystallographic analysis of mutant Escherichia coli aminopeptidase P: insights into substrate recognition and the mechanism of catalysis. Biochemistry. 2006; 45:964-75 [Abstract]

• Graham, S, Bond, C, Freeman, H, Guss, J. Structural and functional implications of metal ion selection in aminopeptidase P, a metalloprotease with a dinuclear metal center. Biochemistry. 2005; 44:13820-36 [Abstract]
• Adams, A, Leong, C, Denny, W, Guss, J. Structures of two minor-groove-binding quinolinium quaternary salts complexed with d(CGCGAATTCGCG)(2) at 1.6 and 1.8 Angstrom resolution. Acta crystallographica. Section D, Biological crystallography. 2005; 61:1348-53 [Abstract]
• Contakes, S, Juda, G, Langley, D, Halpern-Manners, N, Duff, A, Dunn, A, Gray, H, Dooley, D, Guss, J, Freeman, H. Reversible inhibition of copper amine oxidase activity by channel-blocking ruthenium(II) and rhenium(I) molecular wires. Proceedings of the National Academy of Sciences of the United States of America. 2005; 102:13451-6 [Abstract]
• Sträter, N, Jasper, B, Scholte, M, Krebs, B, Duff, A, Langley, D, Han, R, Averill, B, Freeman, H, Guss, J. Crystal structures of recombinant human purple Acid phosphatase with and without an inhibitory conformation of the repression loop. Journal of molecular biology. 2005; 351:233-46 [Abstract]
• Lee, M, Chan, C, Mitchell Guss, J, Christopherson, R, Maher, M. Dihydroorotase from Escherichia coli: loop movement and cooperativity between subunits. Journal of molecular biology. 2005; 348:523-33 [Abstract]

• Deane, J, Ryan, D, Sunde, M, Maher, M, Guss, J, Visvader, J, Matthews, J. Tandem LIM domains provide synergistic binding in the LMO4:Ldb1 complex. The EMBO journal. 2004; 23:3589-98 [Abstract]

• Duff, A, Cohen, A, Ellis, P, Kuchar, J, Langley, D, Shepard, E, Dooley, D, Freeman, H, Guss, J. The crystal structure of Pichia pastoris lysyl oxidase. Biochemistry. 2003; 42:15148-57 [Abstract]

• Bond, C, Blankenship, R, Freeman, H, Guss, J, Maher, M, Selvaraj, F, Wilce, M, Willingham, K. Crystal structure of auracyanin, a "blue" copper protein from the green thermophilic photosynthetic bacterium Chloroflexus aurantiacus. Journal of molecular biology. 2001; 306:47-67 [Abstract]

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